Closing the Diagnostic Gap

The concentration of the protein h-FABP in blood increases rapidly once the cardiac muscle is damaged

Release gradient of cardiac marker

In many cases an increased value can be detected as soon as 30 minutes after onset of symptoms. About 6 hours later h-FABP reaches its peak and returns to its normal level after about 18 to 24 hours.

 

In contrast it takes about 4-6 hours until the classical marker for myocardial infarction Troponin can be detected by bedside tests. Troponin stays elevated for about 10 days.

Diagnostic windows of h-FABP and Troponin

The combination of both marker allows to detect the AMI during the early phase as well as catching the late arrivers. It covers the complete diagnostically relevant time span.

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